Therapeutic indications

In the prevention and treatment of the scalp condition dandruff.

Posology and method of administration

For topical administration.

Adults, elderly and children:

Wash affected areas and leave for 3 to 5 minutes before rinsing.

Treatment:

Wash the hair every 3 or 4 days for 2 to 4 weeks.

Prophylaxis:

Use once, every 1 to 2 weeks.

Do not use more often than directed.

Contraindications

Known hypersensitivity to ketoconazole or any of the excipients

Special warnings and precautions for use

Keep out of the eyes.  If the shampoo should get into the eyes, they should be bathed with water.

In patients who have been on prolonged treatment with topical corticosteroids, it is recommended that the steroid therapy be gradually withdrawn over a period of 2 to 3 weeks, while using Nizoral anti-dandruff Shampoo, to prevent any potential rebound effect.

Seborrhoeic dermatitis and dandruff have been associated with increased hair shedding and this has also been reported, although rarely, with the use of Nizoral anti-dandruff Shampoo.

If the scalp has not cleared within 4 weeks, a doctor or pharmacist should be consulted


Undesirable effects
As with other shampoos, a local burning sensation, itching, or contact dermatitis (due to irritation or allergy) may occur on exposed areas.  Oily and dry hair have been reported rarely with the use of Nizoral anti-dandruff Shampoo.

In rare instances, mainly in patients with chemically damaged hair or grey hair, a discolouration of the hair has been observed with the use of Nizoral anti-dandruff Shampoo.

Additional adverse drug reactions reported in postmarketing reports with Nizoral Anti-dandruff shampoo are included in Table 1.  The frequencies are based on spontaneous reporting rates,